I was testing some flashes in preparation for a shoot tomorrow, and decided that I might as well direct them towards something interesting. The headphones below are actually lit with three flashes. If you picture the headphones as the center of a clock, one flash is sitting about 6" away in the six-o'clock position, with two more about 8" away in the four-o'clock and eight-o'clock positions.
I wanted to get some really sharp detail, so I closed down my aperture a lot. This also darkened the room considerably, and allowed me to control the light hitting my subject almost completely with the flashes. This was not shot in a dark room - the overhead lights were on. However, with the small aperture, only the flash-light mattered.
Again, if you have any questions about off-camera flash, the definitive resource for newbies is Strobist. Work through his Lighting 101 and 102 archives and you will be well on your way.
Canon 5D Mark II
105mm - ISO 400